slideshow 16 slideshow 1 slideshow 2 slideshow 3 slideshow 4 slideshow 5 slideshow 6 slideshow 7 slideshow 8 slideshow 0 slideshow 9 slideshow 10 slideshow 11 slideshow 12 slideshow 13 slideshow 14 slideshow 15

Articles from Wiley

Condividi contenuti
The latest chemistry from ChemPubSoc Europe and Wiley-VCH
Aggiornato: 28 settimane 4 giorni fa

Tuning the Catalytic Activity of Tertiary-Amine Functionalized Polyacrylonitrile Fibers by Adjusting the Surface Microenvironment

26 luglio, 2017 - 00:00

Tuning the Catalytic Activity of Tertiary‐Amine Functionalized Polyacrylonitrile Fibers by Adjusting the Surface Microenvironment

Environmental control: A polyacrylonitrile fiber catalyst, with catalytic activity that can be controlled by tuning the microenvironment polarity, has been designed and applied to a cyanation reaction in water. The catalyst is easy to prepare and has excellent activity (80–98 %) and catalytic recyclability (at least 8 cycles). It also performs well in flow chemistry and scaled-up experiments, which indicates potential applications in industry.

[Full Paper]
Pengyu Li, Yuanyuan Liu, Jian Cao, Minli Tao, Wenqin Zhang
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201700515 Read article

Importance of Ligand Effects Breaking the Scaling Relation for Core–Shell Oxygen Reduction Catalysts

26 luglio, 2017 - 00:00

Importance of Ligand Effects Breaking the Scaling Relation for Core–Shell Oxygen Reduction Catalysts

Ligand effects on ORR: Using transition metal carbides and nitrides as core materials in the form of core-Pt shell catalysts, it is shown that a conventional scaling relation can be broken as a result of significant ligand effects. By comparing ligand and strain effects of core materials, it is demonstrated that the ligand effects effectively cancel out the undesired tensile strain, achieving a comparable ORR activity to Pt with reduced Pt usage.

[Full Paper]
Seoin Back, Yousung Jung
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201700497 Read article

Sustainability and Nanomaterials in Concert

26 luglio, 2017 - 00:00

Sustainability and Nanomaterials in Concert

Nanocatalysts playing the melody of sustainability: The continuous discovery of new heterogeneous catalysts with a nanostructural organization is pushing forward the realization of energy and environmental schemes with sustainability as the common denominator. Hydrogen production, CO2 reduction, and nitrogen fixation are currently some of the most investigated processes aiming at switching the planet to a better lifestyle soon.

[Concept]
Michele Melchionna, Paolo Fornasiero
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201700489 Read article

Electroactivity of NiCr Catalysts for Urea Oxidation in Alkaline Electrolyte

26 luglio, 2017 - 00:00

Electroactivity of NiCr Catalysts for Urea Oxidation in Alkaline Electrolyte

With a large pinch of chromium: The enhanced urea oxidation activity of Ni60Cr40/C compared to that of Ni/C is attributed to its improved charge-transfer kinetics, better dispersion of Ni nuclei, high surface coverage of NiII/NiIII redox center, and a low Tafel slope.

[Full Paper]
Ramesh Kumar Singh, Alex Schechter
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201700451 Read article

RuCl<sub>3</sub> Supported on N-Doped Graphene as a Reusable Catalyst for the One-Step Glucose Oxidation to Succinic Acid

26 luglio, 2017 - 00:00

RuCl3 Supported on N‐Doped Graphene as a Reusable Catalyst for the One‐Step Glucose Oxidation to Succinic Acid

That′s sweet! Glucose is converted in 87 % selectivity to succinic acid under catalytic wet oxidation conditions using ruthenium supported on N-containing graphene as a catalyst without the addition of amines as a co-catalyst.

[Full Paper]
Cristina Rizescu, Iunia Podolean, Bogdan Cojocaru, Vasile I. Parvulescu, Simona M. Coman, Josep Albero, Hermenegildo Garcia
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201700383 Read article

Graphene Quantum Dots Decorated Titania Nanosheets Heterojunction: Efficient Charge Separation and Enhanced Visible-Light Photocatalytic Performance

26 luglio, 2017 - 00:00

 Efficient Charge Separation and Enhanced Visible‐Light Photocatalytic Performance

Joining the dots: Oxygen-functionalized graphene quantum dots (GQDs) are encapsulated into flocculated flexible titania nanosheets (TNSs) to form GQDs/TNSs composite photocatalyst through a facile electrostatic flocculation route. GQDs/TNSs exhibit high photocatalytic activity for the degradation of Rhodamine B under visible light irradiation owing to promoted charge separation.

[Full Paper]
Shiyue Bian, Chenjuan Zhou, Peiran Li, Jiyang Liu, Xiaoping Dong, Fengna Xi
ChemCatChem, July 26, 2017, https://doi.org/10.1002/cctc.201601594 Read article

Recent Advances in Radical Dioxygenation of Olefins

25 luglio, 2017 - 00:00

Recent Advances in Radical Dioxygenation of Olefins

An overview of recent developments in the vicinal dioxygenation of olefins by radical approaches is presented.

[Microreview]
Raghunath Bag, Pinaki Bhusan De, Sourav Pradhan, Tharmalingam Punniyamurthy
Eur. J. Org. Chem., July 25, 2017, https://doi.org/10.1002/ejoc.201700512 Read article

Quantitative Insights into the Fast Pyrolysis of Extracted Cellulose, Hemicelluloses, and Lignin

25 luglio, 2017 - 00:00

Quantitative Insights into the Fast Pyrolysis of Extracted Cellulose, Hemicelluloses, and Lignin

Supergroup: The quantitative mapping of functional groups in fast pyrolysis bio-oil is performed by combining to the use of fast pyrolysis microreactors with spectroscopic techniques and labeling experiments. The results provide a map that displays the distribution of functional groups according to the main constituents of biomass (i.e., hemicelluloses, cellulose and lignin).

[Full Paper]
Marion Carrier, Michael Windt, Bernhard Ziegler, Jörn Appelt, Bodo Saake, Dietrich Meier, Anthony Bridgwater
ChemSusChem, July 25, 2017, https://doi.org/10.1002/cssc.201700984 Read article

An Acid-Responsive Single Trichromatic Luminescent Dye That Provides Pure White-Light Emission

25 luglio, 2017 - 00:00

An Acid‐Responsive Single Trichromatic Luminescent Dye That Provides Pure White‐Light Emission

The butterfly effect: A p-phenylene-bridged bipyrrole bearing N-alkylimino groups exhibits a trichromatic color change in fluorescence from blue to orange to green upon mono- and diprotonation of the imino groups (see figure). The compound demonstrates pure white-light emission as a result of a dynamic equilibrium between the three states.

[Communication]
Keigo Imamura, Yoshifumi Ueno, Seiji Akimoto, Kazuo Eda, Yanqing Du, Chaolu Eerdun, Meiling Wang, Kumiko Nishinaka, Akihiko Tsuda
ChemPhotoChem, July 25, 2017, https://doi.org/10.1002/cptc.201700108 Read article

A Hollow NaGdF<sub>4</sub>/AFn Nanosystem Based on “Relay Race” Release for Therapy

25 luglio, 2017 - 00:00

A Hollow NaGdF4/AFn Nanosystem Based on “Relay Race” Release for Therapy

Pass the baton! We synthesized hollow mesoporous structured NaGdF4 nanoparticles with both excellent upconversion luminescent and magnetic resonance capacities for in vivo imaging applications. The dual-drug system CUR/NaGdF4–DOX/AFn–FA enabled the temporal release of two drugs: curcumin (CUR) is released rapidly to inhibit P-glycoprotein (P-gp) activity and to restore apoptosis signaling pathways, while doxorubicin (DOX) undergoes sustained release and thus high accumulation in drug-resistant cells to exert its therapeutic effect thanks to CUR-mediated inactivation of P-gp.

[Full Paper]
Jie Zhou, Hanchun Yao, Lingchang Meng, Chong Sun, Weiran Ye, Qiuzheng Du
ChemMedChem, July 25, 2017, https://doi.org/10.1002/cmdc.201700295 Read article

Discovery of <sup>wt</sup>RET and <sup>V804M</sup>RET Inhibitors: From Hit to Lead

25 luglio, 2017 - 00:00

 From Hit to Lead

Intentional inhibition: RET kinases are involved in the onset and development of various types of cancer. Currently approved RET inhibitors were not originally designed to be RET inhibitors, and their potency against RET kinase has not been optimized. Starting from our previously identified dual cKIT/PDGFR&#x3B2; inhibitor, we report the development of a novel multi-cKIT/wtRET/V804MRET inhibitor.

[Full Paper]
Luca Mologni, Martina Dalla Via, Adriana Chilin, Manlio Palumbo, Giovanni Marzaro
ChemMedChem, July 25, 2017, https://doi.org/10.1002/cmdc.201700243 Read article

Development of a New Structural Class of Broadly Acting HCV Non-Nucleoside Inhibitors Leading to the Discovery of MK-8876

25 luglio, 2017 - 00:00

Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876

Both palms open: Studies directed at developing a broadly acting non-nucleoside inhibitor of HCV NS5B led to the discovery of a novel structural class of 5-aryl benzofurans that simultaneously interact with both the palm I and palm II binding regions. Herein we describe the efforts that led to the discovery of MK-8876, which advanced into Phase 1 monotherapy studies for evaluation and characterization as a component of an all-oral direct-acting drug regimen for the treatment of chronic HCV infection.

[Full Paper]
Casey C. McComas, Anandan Palani, Wei Chang, M. Katharine Holloway, Charles A. Lesburg, Peng Li, Nigel Liverton, Peter T. Meinke, David B. Olsen, Xuanjia Peng, Richard M. Soll, Ajay Ummat, Jie Wu, Jin Wu, Nicolas Zorn, Steven W. Ludmerer
ChemMedChem, July 25, 2017, https://doi.org/10.1002/cmdc.201700228 Read article

Discovery of Novel Potent Muscarinic M<sub>3</sub> Receptor Antagonists with Proper Plasma Stability by Structural Recombination of Marketed M<sub>3</sub> Antagonists

25 luglio, 2017 - 00:00

Discovery of Novel Potent Muscarinic M3 Receptor Antagonists with Proper Plasma Stability by Structural Recombination of Marketed M3 Antagonists

Steady as she goes: Structural recombination of the marketed muscarinic M3 receptor antagonists aclidinium bromide and glycopyrronium bromide, which have inappropriate plasma stability, led to the discovery of novel potent M3 receptor antagonists 1 a and 1 b, which have proper plasma stability. These antagonists hold great promise as clinical drug candidates to overcome the drawbacks caused by the unsuitable stability of currently marketed M3 antagonists.

[Full Paper]
Zuojuan Xiang, Jun Liu, Hongbin Sun, Xiaoan Wen
ChemMedChem, July 25, 2017, https://doi.org/10.1002/cmdc.201700189 Read article

Critical Evaluation of Native Electrospray Ionization Mass Spectrometry for Fragment-Based Screening

25 luglio, 2017 - 00:00

Critical Evaluation of Native Electrospray Ionization Mass Spectrometry for Fragment‐Based Screening

Does mass matter? Defined sets of fragments were screened against four target proteins by using native mass spectrometry (MS). Beside specific complex formation, many fragments show multiple binding and charge-state shifts. These factors complicate automated data analysis and diminish the attractiveness of native MS as a primary fragment screening tool. However, a comparison of the hits identified by native MS and thermal shift assays shows good agreement for two of the target proteins.

[Full Paper]
Melanie Göth, Volker Badock, Jörg Weiske, Kevin Pagel, Benno Kuropka
ChemMedChem, July 25, 2017, https://doi.org/10.1002/cmdc.201700177 Read article

In Situ Autofluorescence Spectroelectrochemistry for the Study of Microbial Extracellular Electron Transfer

25 luglio, 2017 - 00:00

In Situ Autofluorescence Spectroelectrochemistry for the Study of Microbial Extracellular Electron Transfer

Bacteria studies: In situ autofluorescence spectroelectrochemistry is proposed as a tool to study the extracellular electron transfer (EET) of electrochemically active bacteria. The chemical nature of EET components and potential-dependent structural changes of outer-membrane cytochromes are investigated.

[Article]
Igor Schmidt, Alexander Pieper, Hilke Wichmann, Boyke Bunk, Katharina Huber, Jörg Overmann, Peter Jomo Walla, Uwe Schröder
ChemElectroChem, July 25, 2017, https://doi.org/10.1002/celc.201700675 Read article

High Energy/Power Supercapacitor Performances of Intrinsically Ordered Ruthenium Oxide Prepared through Fast Hydrothermal Synthesis

25 luglio, 2017 - 00:00

High Energy/Power Supercapacitor Performances of Intrinsically Ordered Ruthenium Oxide Prepared through Fast Hydrothermal Synthesis

Time to relax: Considerably improved supercapacitive performance of highly ordered RuO2, obtained through a simple one-step hydrothermal synthesis, is achieved. Owing to fast and uniform microwave heating, regular nanoparticles of well-defined crystalline/amorphous domains with a high surface energy are created. Compact nanoparticulate grains relax into ordered prismoidal clusters, which enhance the availability of charge-exchanging oxide surfaces.

[Article]
Gavrilo &#x160;ekularac, Milica Ko&#x161;evi&#x107;, Aleksandar Dekanski, Veljko Djoki&#x107;, Matja&#x17E; Panjan, Vladimir Pani&#x107;
ChemElectroChem, July 25, 2017, https://doi.org/10.1002/celc.201700609 Read article

Chemically Cross-Linked Poly(2-hydroxyethyl methacrylate)-Supported Deep Eutectic Solvent Gel Electrolytes for Eco-Friendly Supercapacitors

25 luglio, 2017 - 00:00

Chemically Cross‐Linked Poly(2‐hydroxyethyl methacrylate)‐Supported Deep Eutectic Solvent Gel Electrolytes for Eco‐Friendly Supercapacitors

The cure: Highly flexible, low environmental impact energy storage materials. Solid-state deep eutectic solvent gel electrolytes suitable for supercapacitor applications are realized by forming a chemically cross-linked, biocompatible polymer scaffold in situ by UV curing.

[Article]
Huan Qin, Matthew J. Panzer
ChemElectroChem, July 25, 2017, https://doi.org/10.1002/celc.201700586 Read article

Mesoporous Ruthenium/Ruthenium Oxide Thin Films: Active Electrocatalysts for the Oxygen Evolution Reaction

25 luglio, 2017 - 00:00

Mesoporous Ruthenium/Ruthenium Oxide Thin Films: Active Electrocatalysts for the Oxygen Evolution Reaction

On the up: The first synthesis of a fully contiguous large area supported thin film of highly ordered mesoporous Ru and RuO2 is reported. In addition, the electrocatalytic properties towards the oxygen evolution reaction are investigated. This work demonstrates a strategy for engineering materials at the nanoscale that can simultaneously decrease precious metal loading and increase electrode activity.

[Communication]
Jakob Kibsgaard, Thomas R. Hellstern, Shin-Jung Choi, Benjamin N. Reinecke, Thomas F Jaramillo
ChemElectroChem, July 25, 2017, https://doi.org/10.1002/celc.201700334 Read article

Ruthenium-Catalyzed Tandem Activation of C≡N and B−H Bonds under Dihydrogen: Synthesis of BN Heterocycles

25 luglio, 2017 - 00:00

 Synthesis of BN Heterocycles

A new cycle: The synthesis of 1H-benzazaboroles can be achieved from 2-cyanoaryl(amino)boranes through ruthenium-catalyzed C≡N and B−H activation pathways. These BN heterocycles integrate a CH2-NH-B grouping into their structure, and this grouping can be functionalized by N-elementation or by a palladium-catalyzed N-arylation sequence at the B−N bond.

[Communication]
Marion Beguerie, Charly Faradji, Laure Vendier, Sylviane Sabo-Etienne, Gilles Alcaraz
ChemCatChem, July 25, 2017, https://doi.org/10.1002/cctc.201700682 Read article

A High-Throughput Composite Catalyst based on Nickel Carbon Cubes for the Hydrogenation of 5-Hydroxymethylfurfural to 2,5-Dimethylfuran

25 luglio, 2017 - 00:00

A High‐Throughput Composite Catalyst based on Nickel Carbon Cubes for the Hydrogenation of 5‐Hydroxymethylfurfural to 2,5‐Dimethylfuran

A functional nickel-carbon composite catalyst is prepared from porous carbon decorated with nickel nanoparticles. The composite catalyst possesses an unusual nanocube morphology, which allows for a good packing of a fixed-bed flow reactor. The composite cubes are tested for the hydrogenation of 5-hydroxymethylfurfural (HMF) to 2,5-dimethylfuran (DMF) within a continuous-flow setup showing no significant back pressure (&#x394;p≈0 bar).

[Full Paper]
Christian Mbaya Mani, Max Braun, Valerio Molinari, Markus Antonietti, Nina Fechler
ChemCatChem, July 25, 2017, https://doi.org/10.1002/cctc.201700506 Read article

Copyright © 2012 Società Chimica Italiana. All Rights Reserved.