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Articles from Wiley

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The latest papers in Chemistry Europe
Aggiornato: 4 settimane 6 giorni fa

Electronic Modulation between Tungsten Nitride and Cobalt Dopants for Enhanced Hydrogen Evolution Reaction at a Wide Range of pH

27 aprile, 2020 - 00:00

Co doped WN nanowire arrays grown on a carbon cloth are prepared by a facile hydrothermal method and the result shows that the Co dopants can effectively downshift the position of d-band center of W sites as a result of the electron transfer from W to Co thereby decreasing adsorption energy of H on W in Co/WN. Consequently, both of the modulated W and introduced Co dopants facilitate the HER process.

[Communications]
Zhizhong Liu, Prof. Xuming Zhang, Dr. Hao Song, Yixuan Yang, Dr. Yang Zheng, Dr. Biao Gao, Prof. Jijiang Fu, Prof. Paul K. Chu, Prof. Kaifu Huo
doi.org/10.1002/cctc.202000391

Electroless Plating of Transition Metal Boride with High Boron Content as Superior HER Electrocatalyst

27 aprile, 2020 - 00:00

Hydrogen evolution reaction: A strategy of electroless plating of transition metal boride with high boron content to fabricate binder-free catalytic electrode with superior HER activity has been realized.

[Full Papers]
Ruiqi Zhang, Huixiang Liu, Chenfeng Wang, Dr. Lincai Wang, Dr. Yanjing Yang, Dr. Yanhui Guo
doi.org/10.1002/cctc.202000315

Recent Advances in C−H Functionalization with Electrochemistry and Various Iodine-Containing Reagents

27 aprile, 2020 - 00:00

Forming bonds: Organic electrochemistry provides new opportunities for the assembly of various chemical bonds in an environmentally friendly manner. This Minireview summarizes recent advances in electrocatalytic C−H functionalization with various iodine-containing reagents from 2009 to 2019. Previous reports in this field are descried based on the categories of C−X (X=C, N, O, S, etc.) bond formation. The synthetic procedures and possible reaction mechanisms are discussed to provide a better understanding for readers.

[Minireviews]
Dr. Peng Qian, Prof. Zhenggen Zha, Prof. Zhiyong Wang
doi.org/10.1002/celc.202000252

A Critical Analysis about the Underestimated Role of the Electrolyte in Batteries Based on Organic Materials

27 aprile, 2020 - 00:00

The importance of the electrolyte: Redox active organic materials are currently considered as very interesting candidates for the realization of sustainable energy storage devices. This review aims to supply a critical overview about the work carried out so far on the development of electrolytes suitable for these materials.

[Minireviews]
Patrick Gerlach, Prof. Dr. Andrea Balducci
doi.org/10.1002/celc.202000166

Synthesis and SAR of Tetracyclic Inhibitors of Protein Kinase CK2 Derived from Furocarbazole W16

27 aprile, 2020 - 00:00

No get-together: Tetracyclic inhibitors of the protein-protein interaction of the protein kinase CK2 subunits to form the tetrameric holoenzyme have been developed. Particular attention was paid to the stereochemistry and the group X resulting in furo- and pyrrolocarbazoles. Some furocarbazoles showed PPII in the low-micromolar range, inhibition of the tetrameric holoenzyme and weak inhibition of two subunits.

[Full Papers]
Dr. Lukas Kröger, Dr. Constantin G. Daniliuc, Deeba Ensan, Sebastian Borgert, Dr. Christian Nienberg, Miriam Lauwers, Dr. Michaela Steinkrüger, Prof. Joachim Jose, Dr. Markus Pietsch, Prof. Bernhard Wünsch
doi.org/10.1002/cmdc.202000040

Discovery of New Antiproliferative Imidazopyrazole Acylhydrazones Able To Interact with Microtubule Systems

27 aprile, 2020 - 00:00

Two imidazopyrazole carbohydrazides were identified as potential anticancer drugs by preliminary screening of a large library of small molecules against NCI 60 panel cell lines. Further analyses showed their ability to induce apoptosis and affect cell-cycle phases. Immunofluorescence analysis, tubulin polymerization assays and a docking study suggest that the mechanism of action involves the microtubule system.

[Full Papers]
Prof. Chiara Brullo, Dr. Federica Rapetti, Prof. Silvana Alfei, Dr. Irena Maric, Dr. Francesca Rizzelli, Dr. Marina Mapelli, Dr. Camillo Rosano, Dr. Maurizio Viale, Prof. Olga Bruno
doi.org/10.1002/cmdc.202000122

Preclinical Anticancer Activity of an Electron-Deficient Organoruthenium(II) Complex

27 aprile, 2020 - 00:00

Anticancer evaluation: Although electron-deficient, [(p-cymene)Ru(maleonitriledithiolate)] does not interact with the biomolecules that poison a number of organometallic compounds. This half-sandwich complex has remarkable antiproliferative properties, and is cytotoxic to cisplatin-sensitive and -resistant cell lines tested in vitro. Furthermore, some in vivo activity is exhibited in mice.

[Full Papers]
Dr. Joan J. Soldevila-Barreda, Maria Azmanova, Dr. Anaïs Pitto-Barry, Patricia A. Cooper, Dr. Steven D. Shnyder, Prof. Nicolas P. E. Barry
doi.org/10.1002/cmdc.202000096

Structure-Activity Relationship of Phenylpyrazolones against <i>Trypanosoma cruzi</i>

27 aprile, 2020 - 00:00

Testing the scaffold: A series of phenylpyrazolones has been investigated to find compounds that are active against T. cruzi. Although none could match the activity of NPD-0227 (pIC50=6.4), the SAR study turned up valuable data for hit-to-lead optimization and improving the selectivity index, such as the possibility of replacing the pyrazolone moiety by an oxazole or oxadiazole.

[Full Papers]
Maarten Sijm, Dr. Geert Jan Sterk, Prof. Guy Caljon, Prof. Louis Maes, Prof. Iwan J. P. de Esch, Prof. Rob Leurs
doi.org/10.1002/cmdc.202000136

Conducting Redox Polymer as a Robust Organic Electrode-Active Material in Acidic Aqueous Electrolyte towards Polymer-Air Secondary Batteries

27 aprile, 2020 - 00:00

Breathing air into polymers: A polymer-air secondary battery was fabricated with the conducting redox polymer as anode, a conventional Pt/C catalyst as cathode, and sulfuric acid aqueous solution as electrolyte. This battery demonstrated good cycling stability with 97 % capacity retention after 100 cycles and high rate capabilities up to 20 C.

[Full Papers]
Kouki Oka, Christian Strietzel, Dr. Rikard Emanuelsson, Prof. Hiroyuki Nishide, Prof. Kenichi Oyaizu, Prof. Maria Strømme, Prof. Martin Sjödin
doi.org/10.1002/cssc.202000627

First Example of Copper(I) Catalyzed Decarboalkoxymethylation of Alkyl 2-[1-(Pyridin-2-yl)-1<i>H</i>-pyrrol-2-yl]acetates

27 aprile, 2020 - 00:00

An unprecedented functional group assisted CuI-catalyzed defunctionalization reaction has been developed. The simple strategy can remove the ester with the methylene group (-CH2CO2R) from a large array of N-pyridinyl pyrrolo esters. In addition to the synthesis, an interesting extensive mechanistic study with evidence on the roles of both CuI and the N-pyridinyl ring is also reported.

[Communications]
Sk Asraf Ali, Anirban Bera, Susanta Kumar Manna, Subrata Santra, Mijanur Rahaman Molla, Shubhankar Samanta
doi.org/10.1002/ejoc.202000331

Superbase-Mediated Indirect Friedländer Reaction: A Transition Metal-Free Oxidative Annulation toward Functionalized Quinolines

27 aprile, 2020 - 00:00

A transition metal-free superbase mediated indirect Friedländer reaction was developed for accessing functionalized quinolines using o-aminobenzyl alcohol and ketones with an active methylene moiety. The reaction was employed in the functionalization of natural products and the applicability of the reaction for gram-scale synthesis of quinolines was also demonstrated.

[Full Papers]
Rahul P., Nitha P. R., Vishnu K. Omanakuttan, Sheba Ann Babu, P. Sasikumar, Vakayil K. Praveen, Henning Hopf, Jubi John
doi.org/10.1002/ejoc.202000365

Pseudoceroximes A-E and Pseudocerolides A-E - Bromotyrosine Derivatives from a <i>Pseudoceratina</i> sp. Marine Sponge Collected in the South China Sea

27 aprile, 2020 - 00:00

15 new bromotyrosine-derived compounds were isolated from a Pseudoceratina sp. marine sponge collected in the South China Sea. Their structures were assigned by Mosher's method, ECD calculations and X-ray analysis. Pseudoceroximes A (1) and B (2) and pseudocerolide C (8) showed antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 with MIC values of 5.2-7.1 µM.

[Full Papers]
Mengxuan Chen, Yizhen Yan, Hengju Ge, Wei-Hua Jiao, Zhizhen Zhang, Hou-Wen Lin
doi.org/10.1002/ejoc.202000242

Amine- and Amide-Functionalized Mesoporous Carbons: A Strategy for Improving Sulfur/Host Interactions in Li-S Batteries

8 aprile, 2020 - 00:00

Strengthening sulfur-host interactions: A new strategy for improving Li-S cells performance is reported. It tackles by enhancing the adsorption/interactions between Li polysulfides and the working electrode by functionalizing the surface of order mesoporous carbon with amine and amide groups, allowing stronger binding energies and higher energy density of Li-S cells.

[Articles]
Dr. Samuel J. Fretz, Dr. Marco Agostini, Dr. Piotr Jankowski, Prof. Patrik Johansson, Prof. Aleksandar Matic, Prof. Anders E. C. Palmqvist
doi.org/10.1002/batt.202000027

Exosomes as a Source of Cancer Biomarkers: Advances in Electrochemical Biosensing of Exosomes

8 aprile, 2020 - 00:00

“A common insight into a eukaryotic cell: Well-protected strands of DNA are used to create protein-based products and globular proteins, which are a subject to post-translational modification in Golgi (e.g. glycosylation). Mitochondria are providing enough energy for the whole “factory”, while lysosomes remove junk from the cell. One of the common activities of the cell is to release small “packages”—exosomes (containing different substances hidden inside) to other, remote cells.“ Learn more about the story behind the research featured on the front cover in this issue's Cover Profile. Read the corresponding Review at 10.1002/celc.202000075.

[Cover Profile]
Dr. Lenka Lorencova, Dr. Tomas Bertok, Dr. Aniko Bertokova, Veronika Gajdosova, Stefania Hroncekova, Dr. Alica Vikartovska, Dr. Peter Kasak, Dr. Jan Tkac
doi.org/10.1002/celc.202000320

Interface Engineering of MoS<sub>2</sub>-Modified Graphitic Carbon Nitride Nano-photocatalysts for an Efficient Hydrogen Evolution Reaction

8 aprile, 2020 - 00:00

2D/2D nanojunction networks consisting of exfoliated g-C3N4 flakes and 2H MoS2 nanosheets with variable lateral sizes implicate a balanced combination of relatively large number of MoS2 edge sites and efficient electronic transport phenomena at the interfacial contacts. This results in a highly efficient photocatalytic hydrogen production activity of 1497 μmol h−1 gcat−1 and an apparent quantum yield of 3.3 % at 410 nm light irradiation.

[Full Papers]
Eirini D. Koutsouroubi, Ioannis Vamvasakis, Dr. Ioannis T. Papadas, Dr. Charalampos Drivas, Prof. Stelios A. Choulis, Prof. Stella Kennou, Prof. Gerasimos S. Armatas
doi.org/10.1002/cplu.202000096

Photochemistry Relaunched

8 aprile, 2020 - 00:00

[Meet the Board]
Prof. Dr. Christian G. Bochet
doi.org/10.1002/cptc.202000052

Perfluoropyridine as an Efficient, Tunable Scaffold for Bis(pyrazol-1-yl)pyridine Copper Complexes

8 aprile, 2020 - 00:00

Functionalized bis(pyrazol-1-yl)pyridine ligands were synthesized via a 2-step process, utilizing pentafluoropyridine as a pyridine scaffold. The reported method provides ease of control to all substituents, and proceeds under metal-free, mild conditions. The resulting ligands were further utilized in the formation of copper(II) triflate complexes.

[Full Papers]
Andrew J. Peloquin, Matthew B. Houck, Colin D. McMillen, Scott T. Iacono, William T. Pennington
doi.org/10.1002/ejic.202000150

Visible-Light-Promoted Catalytic Ring-Opening Isomerization of 1,2-Disubstituted Cyclopropanols to Linear Ketones

8 aprile, 2020 - 00:00

A visible-light-promoted acridinium-catalyzed radical isomerization of 1,2-disubstituted cyclopropoanols to linear ketones is reported.

[Communications]
Marharyta V. Laktsevich-Iskryk, Nastassia A. Varabyeva, Volha V. Kazlova, Vladimir N. Zhabinskii, Vladimir A. Khripach, Alaksiej L. Hurski
doi.org/10.1002/ejoc.202000094

Selective Conversion of Benzylic Phosphates into Diarylmethanes Through Al(OTf)<sub>3</sub>-Catalyzed Friedel-Crafts-Type Benzylation

8 aprile, 2020 - 00:00

Al(OTf)3 exhibits superior catalyst performance in the Friedel-Crafts-type benzylation using benzylic phosphate as an electrophile. The reaction can be conducted even with 0.2 mol-% of the catalyst. Twenty-one different diarylmethanes are formed. The chemoselective property of the catalyst toward the phosphate group over acetate and bromide is noteworthy.

[Full Papers]
Taiga Yurino, Asuka Hachiya, Keisuke Suzuki, Takeshi Ohkuma
doi.org/10.1002/ejoc.202000077

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