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Green Chem., 2025, Accepted Manuscript
DOI: 10.1039/D5GC04619J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nassim Maarouf-Mesli, Justin Desjardins-michaud, Zeynab IMANI, Kinshuk Ghosh, Felix Polyak, William D Lubell
The demand for sustainable methods for peptide synthesis grows imperatively with their escalating use in therapeutic and biomedical applications. The cornerstone technology of solidphase peptide synthesis has unsustainable environmental impact...
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Green Chem., 2025, Accepted Manuscript
DOI: 10.1039/D5GC05391A, PaperShanquan Liang, Zhiyao Peng, Xue Xia, Kaixing Xiao, Zhao Qin, Xuemei Liu, Fanzhen Lin, Mengdie Wang, Saimeng Jin, James H. Clark, Dan Wang
L-lactate is a basic chemical that widely used in the fields of food, chemistry, and material. Most of L-lactate is produced through microbial fermentation using food crops as materials, which...
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC05322F, PaperDanqing Li, Xin He, Linlin Wang, Mei Ding, Chunhui Gao, Chuankun Jia
The environmental burden of waste asphalt and the performance limitations of sodium-ion battery anodes pose dual challenges in energy and sustainability.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC03448E, PaperFu-Ren Yang, Ye Zheng, Rui-Zhe Deng, Lin Xia, Huai-Ming Wang, Yi-Hao Deng, Wei Situ, Yan-Chun Xiao, Hong-Wei Shen, Jin-Yan Lv, Liu-Song Yu, Hui Wang, Yi-Na Lin, Jian-Wen Ye
Hyperproduction of 3-HB (105 g L−1) was achieved using recombinant EcN with glucose and CO2-derived acetate with a significantly reduced carbon footprint.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04192A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Fathima Fidha, Ashish Kumar, Maria Leko, Oleg Marder, Sergey Burov, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio
2% Methanesulfonic acid (MSA)–formic acid (FA) as a greener substitute for TFA in final global deprotection.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC03906A, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Paul Schweng, Anastasiia Naryshkina, Alexander Blocher, Robert T. Woodward
We report a sustainable approach to the synthesis of hypercrosslinked polymers by replacing conventional chlorinated solvents with renewable bio-based oils.
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Green Chem., 2025, Accepted Manuscript
DOI: 10.1039/D5GC03693C, PaperZhengshan Luo, Xupeng Guo, Zhiwei Deng, Dong Guo, Yan Zhang, Changmei Liu, Zhenbo Yuan, Yijian Rao
Rebaudioside M (Reb M) is an important natural sweetener due to its high sweetness, low calorie content, and pleasant taste, but its low natural abundance and costly, unsustainable extraction limit...
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC03986J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Canan Sener, Emmanuel A. Aboagye, Steven D. Karlen, Jose M. Perez, German E. Umana, Yaoping Zhang, José Serate, Timothy J. Donohue, Daniel R. Noguera, Christos T. Maravelias
Concerted biomass fractionation and lignin depolymerization process integrated with microbial funneling to PDC, ethanol, and electricity results in a 29% reduction in the minimum selling costs for PDC and reduced environmental impact.
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Green Chem., 2025, Accepted Manuscript
DOI: 10.1039/D5GC04622J, PaperSubhajit Saha, Soumya Ranjan Bag, Abdul Akhir, Deepanshi Saxena, Rahul Maitra, Sidharth Chopra, Chandan K. Jana
Indolyl aliphatic N-heterocycles are widely present as the key structural unit of many natural products and unnatural bioactive molecules. The known synthetic methods of indolyl N-heterocycles rely on metallic reagents/catalysts,...
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Green Chem., 2025, Accepted Manuscript
DOI: 10.1039/D5GC04148A, PaperShaoxiong Yang, Yanren Zhu, Enfan Pu, Piaopiao Jiang, Xiong Li, Hongbin Zhang, Jingbo Chen
Linear paired electrolysis is an ideal yet relatively rare electrochemical approach that offers significant advantages for constructing fused heterocyclic frameworks. Herein, we report an efficient protocol for dearomative [3 +...
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04615G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Hidde Kolmeijer, Abhinandan Nabera, Antonio J. Martín, Gonzalo Guillén-Gosálbez, Javier Pérez-Ramírez
This study models a future methanol economy where combining biomass, biogas, and air-captured CO2 achieves net-zero emissions at about 32 USD2025 per person per month, close to Paris Agreement-aligned costs while delivering deeper emission cuts.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04881H, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ren-Guan Miao, Zhi-Peng Bao, Yuanrui Wang, Chang-Sheng Kuai, Xiao-Feng Wu
A novel visible light-induced metal-free carbonylation method for the synthesis of β-trifluoromethylated thioesters has been developed.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04074D, PaperXianda Zhang, Yaotian Yan, Yangshuo Liu, Chun Li, Jian Cao, Junlei Qi
Nafion was recognized as not only a binder component but also a transporter for CO2 on the surface of a metal catalyst.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC02947C, CommunicationJing-Yi Zhang, Ming-Han Li, Yu-Shun Cui, Ying Yang, Miao Lai, Zi-Xun Gao, Lin-Yu Zheng, Si-Ao Lu, Bin-Tao Liu, Fang-Ling Lu, Yu-Lin Feng
A cost-effective and sustainable electrochemical strategy enables highly selective C(sp3)–H functionalization of pyrazolones. 116 valuable novel pyrazolone derivatives were rapidly synthesized under mild conditions.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04609B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Steven W. Thompson, Yasemin Fadil, Nicholas J. Chan, Graeme Moad, Sébastien Perrier, Per B. Zetterlund
Lipoic acid (LA) was successfully incorporated in PBA-b-PSt diblock copolymers via RAFT emulsion polymerization. Films were formed with LA showing minimal effect on mechanical properties. Degradation in DMF results in large molecular weight decrease.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04756K, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sara Grecchi, Andrea Mezzetta, Lorenzo Guazzelli, Serena Arnaboldi
A green and sustainable enantioselective electrosynthesis strategy using a drop of naturally derived chiral ionic liquid, harnessed within a polypyrrole tube microreactor acting as an efficient wireless pump.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC02803E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mood Mohan, Michelle K. Kidder, Jeremy C. Smith
Herein, we report the development of machine learning models for predicting the properties of ionic liquids using Mol2vec featurization technique and this approach enables accelerated development of ILs with optimal properties.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04649A, PaperJingjie Luo, Wenhao Yang, Tao Wang, Hao Liu, Xinyu Mao, Changhai Liang
The transformation of furfural into a variety of high-value-added products attracts a lot of industrial interest and provides a new strategy for the replacement of fossil fuels by available renewable resources.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04034E, PaperYibei Zhang, Hongyun Lu, Xuekai Qu, Lunan Wu, Zhenghao Song, Xinyi Ding, Peng Li, Xiu-Jie Yang, Dong Liu
Solar-driven In2S3–Zn5In2S8 heterostructures enable simultaneous furfuryl alcohol coupling and H2 production without sacrificial agents, offering a green route for biomass valorization and solar fuel coproduction.
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Green Chem., 2025, Advance Article
DOI: 10.1039/D5GC04596G, PaperJinglian Nong, Zehui Cao, Qin He, Yangyang Zhang, Jichao Chen, Yaxin Wang
We have developed a versatile, tunable method for NaNO2/HX (Cl or Br)-mediated radical nitration or vicinal dihalogenation of olefins.
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